Unknown

Dataset Information

0

Chiral isothiourea-catalyzed kinetic resolution of 4-hydroxy[2.2]paracyclophane.


ABSTRACT: We herein report a method for the kinetic resolution of racemic 4-hydroxy[2.2]paracyclophane by means of a chiral isothiourea-catalyzed acylation with isobutyric anhydride. This protocol allows for a reasonable synthetically useful s-factor of 20 and provides a novel entry to obtain this interesting planar chiral motive in an enantioenriched manner.

SUBMITTER: Weinzierl D 

PROVIDER: S-EPMC8042488 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC7540711 | biostudies-literature
| S-EPMC6822272 | biostudies-literature
| S-EPMC4660956 | biostudies-literature
| S-EPMC9306876 | biostudies-literature
| S-EPMC6891757 | biostudies-literature
| S-EPMC7693239 | biostudies-literature
| S-EPMC5911161 | biostudies-literature
| S-EPMC10631200 | biostudies-literature
| S-EPMC8371969 | biostudies-literature
| S-EPMC6270874 | biostudies-literature