Otoacoustic Emissions Evoked by the Time-Varying Harmonic Structure of Speech.
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ABSTRACT:
SUBMITTER: Saiz-Alia M
PROVIDER: S-EPMC8046024 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:The data presented in this article is related to our research article titled "contralateral suppression of transient evoked otoacoustic emissions for various noise signals" (Kalaiah et al., 2017) [1]. The contralateral suppression of transient evoked otoacoustic emissions (TEOAE) was measured from 19 young adults with normal hearing sensitivity. To measure the contralateral suppression, TEOAEs were recorded using clicks in linear mode with and without presenting noise to the contralateral ear. Initially, the TEOAE was recorded without presenting noise to the contralateral ear of participants referred to as 'baseline' TEOAE. Following this, the TEOAE was recorded by presenting noise to the contralateral ear, referred to as contralateral noise conditions. Noises used in the present study included white noise, amplitude-modulated noise, and real-life noise signals. All recordings were completed on the same session in single probe-fit condition. The data reported here include the global amplitude of TEOAE, noise-floor level, and signal-to-noise ratio across baselines and contralateral noise conditions and the magnitude of contralateral suppression for various noises. Further, the data includes the amplitude of TEOAEs and suppression magnitude across eight 2 ms time bands between 2 and 18 ms.
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Project description:OBJECTIVES:The purpose of this study was to analyze distortion product otoacoustic emission (DPOAE) level and signal to noise ratio in a group of infants from birth to 4 months of age to optimize prediction of hearing status. DPOAEs from infants with normal hearing (NH) and hearing loss (HL) were used to predict the presence of conductive HL (CHL), sensorineural HL (SNHL), and mixed HL (MHL). Wideband ambient absorbance was also measured and compared among the HL types. DESIGN:This is a prospective, longitudinal study of 279 infants with verified NH and HL, including conductive, sensorineural, and mixed types that were enrolled from a well-baby nursery and two neonatal intensive care units in Cincinnati, Ohio. At approximately 1 month of age, DPOAEs (1-8?kHz), wideband absorbance (0.25-8?kHz), and air and bone conduction diagnostic tone burst auditory brainstem response (0.5-4?kHz) thresholds were measured. Hearing status was verified at approximately 9 months of age with visual reinforcement audiometry (0.5-4?kHz). Auditory brainstem response air conduction thresholds were used to assign infants to an NH or HL group, and the efficacy of DPOAE data to classify ears as NH or HL was analyzed using receiver operating characteristic (ROC) curves. Two summary statistics of the ROC curve were calculated: the area under the ROC curve and the point of symmetry on the curve at which the sensitivity and specificity were equal. DPOAE level and signal to noise ratio cutoff values were defined at each frequency as the symmetry point on their respective ROC curve, and DPOAE results were combined across frequency in a multifrequency analysis to predict the presence of HL. RESULTS:Single-frequency test performance of DPOAEs was best at mid to high frequencies (3-8?kHz) with intermediate performance at 1.5 and 2?kHz and chance performance at 1?kHz. Infants with a conductive component to their HL (CHL and MHL combined) displayed significantly lower ambient absorbance values than the NH group. No differences in ambient absorbance were found between the NH and SNHL groups. Multifrequency analysis resulted in the best prediction of HL for the SNHL/MHL group with poorer sensitivity values when infants with CHL were included. CONCLUSIONS:Clinical interpretation of DPOAEs in infants can be improved by using age-appropriate normative ranges and optimized cutoff values. DPOAE interpretation is most predictive at higher F2 test frequencies in young infants (2-8?kHz) due to poor test performance at 1 to 1.5?kHz. Multifrequency rules can be used to improve sensitivity while balancing specificity. Last, a sensitive middle ear measure such as wideband absorbance should be included in the test battery to assess possibility of a conductive component to the HL.
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