Ontology highlight
ABSTRACT:
SUBMITTER: Brown JR
PROVIDER: S-EPMC8053833 | biostudies-literature | 2021 Jan-Dec
REPOSITORIES: biostudies-literature
Brown Jason R JR Krane Spencer S Garcia Jorge J Barata Pedro C PC
Therapeutic advances in urology 20210101
Immune checkpoint inhibition has been approved for front-line treatment of metastatic bladder cancer in patients who are cisplatin-ineligible and demonstrate programmed death-ligand 1 (PD-L1) positivity. This approval followed the positive results of IMvigor210 and KEYNOTE-052 studies. Immunotherapy has also demonstrated efficacy as maintenance therapy patients for patients who initially respond to platinum-based chemotherapy. Other studies have investigated combinations of immunotherapy with ch ...[more]