Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.
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SUBMITTER: Harris WS
PROVIDER: S-EPMC8062567 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
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Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.
Harris William S WS Tintle Nathan L NL Imamura Fumiaki F Qian Frank F Korat Andres V Ardisson AVA Marklund Matti M Djoussé Luc L Bassett Julie K JK Carmichael Pierre-Hugues PH Chen Yun-Yu YY Hirakawa Yoichiro Y Küpers Leanne K LK Laguzzi Federica F Lankinen Maria M Murphy Rachel A RA Samieri Cécilia C Senn Mackenzie K MK Shi Peilin P Virtanen Jyrki K JK Brouwer Ingeborg A IA Chien Kuo-Liong KL Eiriksdottir Gudny G Forouhi Nita G NG Geleijnse Johanna M JM Giles Graham G GG Gudnason Vilmundur V Helmer Catherine C Hodge Allison A Jackson Rebecca R Khaw Kay-Tee KT Laakso Markku M Lai Heidi H Laurin Danielle D Leander Karin K Lindsay Joan J Micha Renata R Mursu Jaako J Ninomiya Toshiharu T Post Wendy W Psaty Bruce M BM Risérus Ulf U Robinson Jennifer G JG Shadyab Aladdin H AH Snetselaar Linda L Sala-Vila Aleix A Sun Yangbo Y Steffen Lyn M LM Tsai Michael Y MY Wareham Nicholas J NJ Wood Alexis C AC Wu Jason H Y JHY Hu Frank F Sun Qi Q Siscovick David S DS Lemaitre Rozenn N RN Mozaffarian Dariush D
Nature communications 20210422 1
The health effects of omega-3 fatty acids have been controversial. Here we report the results of a de novo pooled analysis conducted with data from 17 prospective cohort studies examining the associations between blood omega-3 fatty acid levels and risk for all-cause mortality. Over a median of 16 years of follow-up, 15,720 deaths occurred among 42,466 individuals. We found that, after multivariable adjustment for relevant risk factors, risk for death from all causes was significantly lower (by ...[more]
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