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In vitro activity of tedizolid against linezolid-resistant staphylococci and enterococci.

ABSTRACT: The tedizolid MIC of 27 clinical isolates of linezolid-resistant staphylococci and enterococci was determined. Tedizolid MICs were ≥1μg/mL and were 4- to 32-fold lower than those of linezolid. Linezolid resistance mechanisms included G2576T 23S rRNA gene and rplC and rplD mutations.

SUBMITTER: Silva-Del Toro SL 

PROVIDER: S-EPMC8067670 | biostudies-literature |

REPOSITORIES: biostudies-literature

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