Coeliac disease is associated with depression in children and young adults with type 1 diabetes: results from a multicentre diabetes registry.

ABSTRACT:

Aims

To analyse the association between coeliac disease (CD) and depression in children, adolescents, and young adults with type 1 diabetes (T1D).

Methods

We included 79,067 T1D patients aged 6-20 years, with at least six months of diabetes duration, and treatment data between 1995 and 2019 were documented in the diabetes patient follow-up registry. We categorized patients into four groups: T1D only (n = 73,699), T1 + CD (n = 3379), T1D + depression (n = 1877), or T1D + CD + depression (n = 112).

Results

CD and depression were significantly associated (adjusted OR: 1.25 [1.03-1.53]). Females were more frequent in both the depression and the CD group compared with the T1D only group. Insulin pumps were used more frequently in T1D + CD and T1D + depression compared with

SUBMITTER: Tittel SR 

PROVIDER: S-EPMC8076130 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature