Dataset Information

Ultrasound-Guided Fine-Needle Aspiration Versus Fine-Needle Capillary Sampling in Evaluation of Lymph Node Metastasis of Thyroid Cancer.

ABSTRACT:

Background

To compare the sampling adequacy and diagnostic efficiency of ultrasound-guided fine-needle aspiration with 22-, 25-gauge needles and capillary sampling with 22-gauge needle in the biopsy of cervical lymph node.

Methods

A total of 130 cervical lymph nodes from 103 patients were consecutively included in the prospective study. Each suspected lymph node was aspirated with a 22-gauge needle, capillary sampled with a 22-gauge needle and aspirated with a 25-gauge needle. The adequacy rates and nondiagnostic rates of obtained specimen were calculated.

Results

Of the 130 suspected lymph nodes, there were 77 lymph nodes<6.0 mm and 53 lymph nodes≥6.0mm in the smallest dimension. Both FNA_22G and FNC_22G got significantly higher sampling adequacy than FNA_25G for the total lymph nodes. For lymph nodes<6.0 mm, the sampling adequacy was significantly higher with FNA_22G than with FNA_25G for each parameter and the cumulative score (all P<0.05), while no difference were seen between FNA_22G and FNC_22G, and between FNC_22G and FNA_25G. There were higher nondiagnostic rates for FNA_25G compared with FNA_22G and FNC_22G in all lymph nodes and in each size subgroups. FNA_25G yielded more diagnostically inadequate specimens than FNA_22G and FNC_22G did in the total lymph nodes (P=0.002), in lymph nodes<6.0 mm (P=0.014), and in those ≥ 6.0 mm (P=0.000).

Conclusions

FNA_22G and FNC_22G obtained more diagnostically adequate specimens than FNA_25G in cervical lymph nodes. FNA_22G and FNC_22G may be more suitable than FNA_25G in diagnosing cervical lymph nodes. FNA_22G and FNC_22G may yield specimens with similar quality.

SUBMITTER: Xia S

PROVIDER: S-EPMC8079778 | biostudies-literature |

REPOSITORIES: biostudies-literature

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