Ontology highlight
ABSTRACT:
SUBMITTER: Lee SS
PROVIDER: S-EPMC8100193 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Lee Sang Soo SS Adams Michael E ME
Frontiers in neuroscience 20210422
Endocrine state is an important determinant of learning and memory in animals. In <i>Drosophila</i>, rejection of male courtship overtures by mated females leads to an aversive response manifested as courtship memory. Here we report that ecdysis triggering hormone (ETH) is an obligatory enabler of long-term courtship memory (LTM). ETH deficiency suppresses LTM, whereas augmented ETH release reduces the minimum training period required for LTM induction. ETH receptor knockdown either in the mushr ...[more]