Dataset Information

Clinical course and outcome of patients with COVID-19 in Mumbai City: an observational study.

ABSTRACT:

Objective

To understand the outcome of hospitalised patients from Mumbai City, which had the highest number of COVID-19 cases in India.

Design

Observational study with follow-up.

Setting

Data extraction from medical records of patients with COVID-19 admitted to Nair Hospital & TN Medical College, Mumbai, India.

Participants

689 patients with COVID-19 were admitted in the hospital from 26 March 2020 to 11 May 2020.

Primary and secondary outcome measures

In-hospital mortality; joint effect of comorbidity and age on the risk of dying.

Results

A total of 689 patients (median age 44 years) admitted with RT-PCR-confirmed COVID-19 were included in the study. Of these, 77.36% of patients were discharged alive while 22.64% died. 11.61% required some kind of oxygen support while 2.8% of patients required intensive care unit admissions. Older age (HR 2.88, 95% CI 2.09 to 3.98), presence of comorbidities (HR 2.56, 95% CI 1.84 to 3.55), history of hypertension (HR 3.19, 95% CI 1.67 to 6.08), and presence of symptoms at the time of admission (HR 3.21, 95% CI 1.41 to 7.26) were associated with increased risk of in-hospital mortality. Treatment with a combination of azithromycin with hydroxychloroquine, antiviral or steroid compared with no treatment did not alter the disease course and in-hospital mortality. The combined effect of old age and presence of comorbid conditions was more pronounced in women than men.

Conclusions

In-hospital patients were younger, less symptomatic with lesser need of ventilators and oxygen support as compared with many western countries.

Trial registration

Not applicable (observational study, not a clinical trial).

SUBMITTER: de Souza R

PROVIDER: S-EPMC8103559 | biostudies-literature |

REPOSITORIES: biostudies-literature

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