Large-scale screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) among healthcare workers: Prevalence and risk factors for asymptomatic and pauci-symptomatic carriers, with emphasis on the use of personal protective equipment (PPE).
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ABSTRACT:
SUBMITTER: Rajme-Lopez S
PROVIDER: S-EPMC8111176 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:With numerous countermeasures, the number of deaths in the construction industry is still higher compared to other industries. Personal Protective Equipment (PPE) is constantly being improved to avoid these accidents, although workers intentionally or unintentionally forget to use such safety measures. It is challenging to manually run a safety check as the number of co-workers on a site can be large; however, it is a prime duty of the authority to provide maximum protection to the workers on the working site. From these motivations, we have created a computer vision (CV) based automatic PPE detection system that detects various types of PPE. This study also created a novel dataset named CHVG (four colored hardhats, vest, safety glass) containing eight different classes, including four colored hardhats, vest, safety glass, person body, and person head. The dataset contains 1,699 images and corresponding annotations of these eight classes. For the detection algorithm, this study has used the You Only Look Once (YOLO) family's anchor-free architecture, YOLOX, which yields better performance than the other object detection models within a satisfactory time interval. Moreover, this study found that the YOLOX-m model yields the highest mean average precision (mAP) than the other three versions of the YOLOX.
| S-EPMC9299268 | biostudies-literature
Project description:We modeled the stability of SARS-CoV-2 on personal protective equipment (PPE) commonly worn in hospitals when carrying out high-risk airway procedures. Evaluated PPE included the visors and hoods of two brands of commercially available powered air purifying respirators, a disposable face shield, and Tyvek coveralls. Following an exposure to 4.3 log10 plaque-forming units (PFUs) of SARS-CoV-2, all materials displayed a reduction in titer of > 4.2 log10 by 72 hours postexposure, with detectable titers at 72 hours varying by material (1.1-2.3 log10 PFU/mL). Our results highlight the need for proper doffing and disinfection of PPE, or disposal, to reduce the risk of SARS-CoV-2 contact or fomite transmission.
| S-EPMC7866333 | biostudies-literature
Project description:During the doffing of personal protective equipment (PPE), pathogens can be transferred from the PPE to the bodies of healthcare workers (HCWs), putting HCWs and patients at risk of exposure and infection. PPE doffing practices of HCWs who cared for patients with viral respiratory infections were observed at an acute care hospital from March 2017 to April 2018. A trained observer recorded doffing performance of HCWs inside the patient rooms using a pre-defined checklist based on the Centers for Disease Control and Prevention (CDC) guideline. Doffing practices were observed 162 times during care of 52 patients infected with respiratory viral pathogens. Out of the 52 patients, 30 were in droplet and contact isolation, 21 were in droplet isolation, and 1 was in contact isolation. Overall, 90% of observed doffing was incorrect, with respect to the doffing sequence, doffing technique, or use of appropriate PPE. Common errors were doffing gown from the front, removing face shield of the mask, and touching potentially contaminated surfaces and PPE during doffing. Deviations from the recommended PPE doffing protocol are common and can increase potential for contamination of the HCW's clothing or skin after providing care. There is a clear need to change the approach used to training HCWs in PPE doffing practices.
| S-EPMC7157959 | biostudies-literature
Project description:ObjectivesTo assess prevalence of Personal Protective Equipment (PPE)-related symptoms and adverse reactions during Coronavirus Disease 2019 pandemics.MethodsWe conducted an observational study among people exposed to various degree of infectious risk. Data were collected with a self-administered online questionnaire.ResultsThe entire cohort complained about a wide range of adverse reactions: respiratory symptoms affected 80.3% of respondents, 68.5% referred pressure-related skin lesions, fewer manifested a dermatosis of different grade or ocular symptoms. Most of the affected individuals belonged to healthcare staff and manifestations were predicted by wearing time (more than 6 h/d). Moreover, symptoms were higher in the healthcare staff wearing N95/FFP2 respirator mask.ConclusionsGiven the crucial role of PPE to contain the pandemic infection, more attention has to be paid to exposed categories, establishing preventive measure of side effects to ensure total safety.
| S-EPMC7864606 | biostudies-literature
Project description:PurposeIn the absence of vaccine, proper use of personal protective equipment (PPE) is the most important strategy to protect healthcare workers against COVID-19 infection. The recommendations on pharmacological prophylaxis against COVID-19 infection are controversial. The aim of current study was to assess PPE practices during surgery on COVID-19 negative gynecological cancer patients and use of pharmacologic prophylaxis by clinicians practicing gynecologic oncology.MethodsWe disbursed a survey questionnaire through various social media platforms among clinicians practicing gynecologic oncology. The survey consisted of 37 questions divided into five subgroups evaluating demographic details, use of pharmacological prophylaxis against COVID-19, preoperative COVID-19 screening protocol, details on PPE usage and associated discomfort, if any.ResultsTwo hundred twenty oncologists from 13 countries responded to the survey. Pharmacological prophylaxis was being used by 85 (38.6%) respondents; most common agent was hydroxychloroquin (HCQ) by 24.5% respondents. Routine preoperative screening for COVID-19 was performed by 214 (97.3%) respondents. Some degree of discomfort during surgery due to PPE use was reported by 170 (77.3%) respondents, which was moderate to severe in 73 (33.2%) respondents. Most common difficulties associated with face mask/shield were problems in communication (69.5%) and breathing (58.1%). Eye protection was associated with poor visibility, fogging and headache. Unusual fatigue attributed to PPE use was experienced by 143(65%) respondents.ConclusionUse of pharmacological prophylaxis against COVID-19 is controversial and the same is reflected in our survey. Most respondents adhered to PPE use despite experiencing some physical discomfort.Supplementary informationThe online version contains supplementary material available at 10.1007/s40944-021-00500-4.
| S-EPMC7847240 | biostudies-literature
Project description:Background270 million workplace accidents occur annually. In Uganda, Kampala district has the highest workplace injury and fatality rates. However, information on personal protective equipment (PPE)-hand gloves, hardhats, overalls, safety boots, earplugs, safety harness with lanyard, and face shields-utilization among building construction workers remains scarce. We assessed PPE utilization and determinants among building construction workers in Kampala, Uganda.MethodsThis cross-sectional study involved 385 respondents. Data collected by structured questionnaire was double-entered in EpiData and analyzed in STATA at 5% significance level. Independent determinants of PPE use were established by a stepwise backward logistic regression analysis.Results305 (79.2%) respondents were males, 290 (75.3%) were 18-30 years, 285 (74.0%) completed secondary education, and 197 (51.2%) were temporary employees. 60 (15.6%) respondents used PPE. Female sex (adjusted odds ratio (AOR) = 6.64; 95% CI: 1.55-28.46; P = 0.011), temporary (AOR = 0.05; 95% CI: 0.01-0.27; P < 0.001) and casual (AOR = 0.01; 95% CI: 0.001-0.071; P < 0.001) employment, and previous knowledge of safety measures (AOR = 100.72; 95% CI: 26.00-390.16; P < 0.001) were associated with PPE use.ConclusionPPE use was low in Kampala, Uganda. Building construction companies should implement measures of the Uganda Occupational Health and Safety Act.
| S-EPMC5672632 | biostudies-literature
Project description:Aim:We investigated personal protective equipment (PPE) use and its shortage, training, and adverse events among healthcare workers (HCWs) in the intensive care unit (ICU) during the coronavirus disease (COVID-19) pandemic in Japan and compared the results with an international survey that used the same methodology. Methods:This web-based survey was conducted from April 14 to May 6, 2020, in Japan and included HCWs directly involved in ICU management of COVID-19 patients. A survey invitation was emailed using the Japanese Society of Intensive Care Medicine's mailing list. Results:We analyzed 460 valid responses from among 976 responses. The N95/FFP2 mask (77%) was most frequently used than in the international study, although half of our respondents reported reuse of single-use N95/FFP2 masks. The median duration (1 hour) of uninterrupted PPE use per shift was less than that in the international study. The commonest PPE-related adverse event was experiencing intense heat (75%). Logistic regression analysis revealed that being a nurse was independently associated with experiencing intense heat. Conclusion:PPE shortage and frequent mask reuse were prevalent during the COVID-19 pandemic in Japan. Intense heat is the most significant symptom, especially for nurses, even with short-duration PPE use. Strategies to protect HCWs from dehydration and intense heat stroke are needed.
| S-EPMC7537292 | biostudies-literature
Project description:The use and disposal of face masks, gloves, face shields, and other types of personal protective equipment (PPE) have increased dramatically due to the ongoing COVID-19 pandemic. Many governments enforce the use of PPE as an efficient and inexpensive way to reduce the transmission of the virus. However, this may pose a new challenge to solid waste management and exacerbate plastic pollution. The aim of the present study was to report the occurrence and distribution of COVID-19-associated PPE along the coast of the overpopulated city of Lima, Peru, and determine the influence of the activities carried out in each study site. In general terms, 138 PPE items were found in 11 beaches during 12 sampling weeks. The density was in the range of 0 to 7.44 × 10-4 PPE m-2. Microplastic release, colonization of invasive species, and entanglement or ingestion by apex predators are some of the potential threats identified. Recreational beaches were the most polluted sites, followed by surfing, and fishing sites. This may be because recreational beaches are many times overcrowded by beachgoers. Additionally, most of the PPE was found to be discarded by beachgoers rather than washed ashore. The lack of environmental awareness, education, and coastal mismanagement may pose a threat to the marine environment through marine litter and plastic pollution. Significant efforts are required to shift towards a sustainable solid waste management. Novel alternatives involve redesigning masks based on degradable plastics and recycling PPE by obtaining liquid fuels through pyrolysis.
| S-EPMC7875711 | biostudies-literature
Project description:Pandemics and re-emerging diseases put pressure on the health care system to prepare for patient care and sample logistics requiring enhanced personnel protective equipment (PPE) for health care workers. We generated quantifiable data on ergonomics of PPE applicable in a health care setting by defining error rates and physically limiting factors due to PPE-induced restrictions. Nineteen study volunteers tested randomly allocated head- or full body-ventilated PPE suits equipped with powered-air-purifying-respirators and performed four different tasks (two laboratory tutorials, a timed test of selective attention and a test investigating reaction time, mobility, speed and physical exercise) during 6 working hours at 22°C on one day and 4 working hours at 28°C on another day. Error rates and physical parameters (fluid loss, body temperature, heart rate) were determined and ergonomic-related parameters were assessed hourly using assessment sheets. Depending on the PPE system the most restrictive factors, which however had no negative impact on performance (speed and error rate), were: reduced dexterity due to multiple glove layers, impaired visibility by flexible face shields and back pain related to the respirator of the fully ventilated suit. Heat stress and liquid loss were perceived as restrictive at a working temperature of 28°C but not 22°C.
| S-EPMC6342303 | biostudies-literature
Project description:BackgroundHealthcare workers (HCWs) use personal protective equipment (PPE) in Ebola virus disease (EVD) situations. However, preventing the contamination of HCWs and the environment during PPE removal crucially requires improved strategies. This study aimed to compare the efficacy of three PPE ensembles, namely, Hospital Authority (HA) Standard Ebola PPE set (PPE1), Dupont Tyvek Model, style 1422A (PPE2), and HA isolation gown for routine patient care and performing aerosol-generating procedures (PPE3) to prevent EVD transmission by measuring the degree of contamination of HCWs and the environment.MethodsA total of 59 participants randomly performed PPE donning and doffing. The trial consisted of PPE donning, applying fluorescent solution on the PPE surface, PPE doffing of participants, and estimation of the degree of contamination as indicated by the number of fluorescent stains on the working clothes and environment. Protocol deviations during PPE donning and doffing were monitored.ResultsPPE2 and PPE3 presented higher contamination risks than PPE1. Environmental contaminations such as those originating from rubbish bin covers, chairs, faucets, and sinks were detected. Procedure deviations were observed during PPE donning and doffing, with PPE1 presenting the lowest overall deviation rate (%) among the three PPE ensembles (p < 0.05).ConclusionContamination of the subjects' working clothes and surrounding environment occurred frequently during PPE doffing. Procedure deviations were observed during PPE donning and doffing. Although PPE1 presented a lower contamination risk than PPE2 and PPE3 during doffing and protocol deviations, the design of PPE1 can still be further improved. Future directions should focus on designing a high-coverage-area PPE with simple ergonomic features and on evaluating the doffing procedure to minimise the risk of recontamination. Regular training for users should be emphasised to minimise protocol deviations, and in turn, guarantee the best protection to HCWs.
| S-EPMC6303998 | biostudies-literature