Ontology highlight
ABSTRACT:
SUBMITTER: Engelmann P
PROVIDER: S-EPMC8139402 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Engelmann Péter P Farkas Klára K Kis János J Richman Geoffrey G Zhang Zhaoyun Z Liew Chong Wee CW Borowiec Maciej M Niewczas Monika A MA Jalahej Heyam H Orbán Tihamér T
International immunology 20110627 8
Recently described forkhead box protein 3 (FoxP3) transcription factor is a key molecule in CD4+ CD25hi+ T-cell characterization. Invariant NK T (iNKT) cells are also characterized as regulatory cells modulating the immune response by rapidly producing T(h)1 and T(h)2 cytokines. We aimed to analyze cellular markers important in regulatory features of human iNKT cells and to study their role in functional assays. iNKT cells were single cell sorted from peripheral mononuclear cells of healthy indi ...[more]