External induction and stabilization of brain oscillations in the human.

ABSTRACT:

Background

Neural oscillations in the cerebral cortex are associated with a range of cognitive processes and neuropsychiatric disorders. However, non-invasively modulating oscillatory activity remains technically challenging, due to limited strength, duration, or non-synchronization of stimulation waveforms with endogenous rhythms.

Objective

We hypothesized that applying controllable phase-synchronized repetitive transcranial magnetic stimulation pulses (rTMS) with alternating currents (tACS) may induce and stabilize neuro-oscillatory resting-state activity at targeted frequencies.

Methods

Using a novel circuit to precisely synchronize rTMS pulses with phase of tACS, we empirically tested whether combined, 10-Hz prefrontal bilateral stimulation could induce and stabil

SUBMITTER: Hosseinian T 

PROVIDER: S-EPMC8144019 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature