Modular barcode beads for microfluidic single cell genomics.
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ABSTRACT:
SUBMITTER: Delley CL
PROVIDER: S-EPMC8149635 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Publications
Modular barcode beads for microfluidic single cell genomics.
Delley Cyrille L CL Abate Adam R AR
Scientific reports 20210525 1
Barcode beads allow efficient nucleic acid tagging in single cell genomics. Current barcode designs, however, are fabricated with a particular application in mind. Repurposing to novel targets, or altering to add additional targets as information is obtained is possible but the result is suboptimal. Here, we describe a modular framework that simplifies generation of multifunctional beads and allows their easy extension to new targets. ...[more]
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