Ontology highlight
ABSTRACT:
SUBMITTER: Poorbahrami K
PROVIDER: S-EPMC8159973 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Poorbahrami Kamran K Vignon-Clementel Irene E IE Shadden Shawn C SC Oakes Jessica M JM
Scientific reports 20210527 1
Anatomical and physiological changes alter airflow characteristics and aerosol distribution in the developing lung. Correlation between age and aerosol dosimetry is needed, specifically because youth are more susceptible to medication side effects. In this study, we estimate aerosol dosages (particle diameters of 1, 3, and 5 [Formula: see text]m) in a 3 month-old infant, a 6 year-old child, and a 36 year-old adult by performing whole lung subject-specific particle simulations throughout respirat ...[more]