A novel somatosensory spatial navigation system outside the hippocampal formation.

ABSTRACT: Spatially selective firing of place cells, grid cells, boundary vector/border cells and head direction cells constitutes the basic building blocks of a canonical spatial navigation system centered on the hippocampal-entorhinal complex. While head direction cells can be found throughout the brain, spatial tuning outside the hippocampal formation is often non-specific or conjunctive to other representations such as a reward. Although the precise mechanism of spatially selective firing activity is not understood, various studies show sensory inputs, particularly vision, heavily modulate spatial representation in the hippocampal-entorhinal circuit. To better understand the contribution of other sensory inputs in shaping spatial representation in the brain, we performed recording from the prima

SUBMITTER: Long X 

PROVIDER: S-EPMC8169756 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature