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FGF23 and Cause-Specific Mortality in Community-Living Individuals-The Health, Aging, and Body Composition Study.


ABSTRACT:

Objectives

Fibroblast growth factor (FGF)-23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C-terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause-specific mortality is unknown.

Design

Prospective analyses of data from Health, Aging, & Body Composition (HABC) study.

Setting

Community-living adults aged 70 to 79 years with longitudinal follow up.

SUBMITTER: Sharma S 

PROVIDER: S-EPMC8175094 | biostudies-literature |

REPOSITORIES: biostudies-literature

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