FGF23 and Cause-Specific Mortality in Community-Living Individuals-The Health, Aging, and Body Composition Study.
Ontology highlight
ABSTRACT: Objectives
Fibroblast growth factor (FGF)-23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C-terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause-specific mortality is unknown.Design
Prospective analyses of data from Health, Aging, & Body Composition (HABC) study.Setting
Community-living adults aged 70 to 79 years with longitudinal follow up.
SUBMITTER: Sharma S
PROVIDER: S-EPMC8175094 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
FGF23 and Cause-Specific Mortality in Community-Living Individuals-The Health, Aging, and Body Composition Study.
Sharma Shilpa S Katz Ronit R Dubin Ruth F RF Drew David A DA Gutierrez Orlando M OM Shlipak Michael G MG Sarnak Mark J MJ Ix Joachim H JH
Journal of the American Geriatrics Society 20201110 3
<h4>Objectives</h4>Fibroblast growth factor (FGF)-23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C-terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause-specific mortality is unknown.<h4>Design</h4>Prospective analyses of data from Health, Aging, & Body Composition (HABC) study.<h4>Setting</h4>Commu ...[more]
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