Renal allograft function in kidney transplant recipients infected with SARS-CoV 2: An academic single center experience.

ABSTRACT:

Background

Kidney transplant recipients are a unique cohort in regard to SARS-CoV 2 susceptibility and clinical course, owing to their immunosuppressed state and propensity for kidney injury. The primary purpose of this study is to ascertain if, in kidney transplant recipients, SARS-CoV 2 infection impacts long term renal allograft function.

Methods

This retrospective, single-center study reviewed 53 kidney transplant recipients with a positive SARS-CoV-2 PCR at NMH from January 1, 2020 to June 30, 2020.

Results

Change in eGFR from baseline kidney function prior to infection to 90 days after the first positive SARS-CoV 2 test was +1.76%, -17.5% and -23.16% the mild, moderate and severe disease groups respectively. There was a significant decline in kidney function in

SUBMITTER: Nahi SL 

PROVIDER: S-EPMC8191896 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature