Temporal organisation of the brain's intrinsic motor network: The relationship with circadian phenotype and motor performance.

ABSTRACT:

Background

Functional connectivity (FC) of the motor network (MN) is often used to investigate how intrinsic properties of the brain are associated with motor abilities and performance. In addition, the MN is a key feature in clinical work to map the recovery after stroke and aid the understanding of neurodegenerative disorders. Time of day variation and individual differences in circadian timing, however, have not yet been considered collectively when looking at FC.

Methods

A total of 33 healthy, right handed individuals (13 male, 23.1 ± 4.2 years) took part in the study. Actigraphy, sleep diaries and circadian phase markers (dim light melatonin onset and cortisol awakening response) were used to determine early (ECP, n = 13) and late (LCP, n = 20) circadian phenotype group

SUBMITTER: Facer-Childs ER 

PROVIDER: S-EPMC8214225 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature