Ontology highlight
ABSTRACT: Background
Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown. This study investigated changes of chronic Capsiate supplementation on muscular adaptations, inflammatory response and performance in untrained men.Methods
Twenty untrained men were randomized to ingest 12 mg Capsiate (CAP) or placebo in a parallel, double-blind design. Body composition and performance were measured at pre-training and after 6 weeks of resistance training. An acute resistance exercise session test was performed pre and post-intervention. Blood samples were collected at rest and post-resistance exercise to analyze Tumor necrosis factor- (TNF-), Soluble TNF- receptor (sTNF-r), Interleukin-6 (IL-6) and Interleukin-10 (IL-10).Results
Exercise and CAP supplementation increased fat-free mass in comparison to baseline by 1.5 kg (P < 0.001), however, the majority of the increase (1.0 kg) resulted from an increase in total body water. The CAP change scores for fat-free mass were significantly greater in comparison to the placebo (CAP ∆%= 2.1 ± 1.8 %, PLA ∆%= 0.7 ± 1.3 %, P = 0.043) and there was a significant difference between groups in the bench press exercise (P = 0.034) with greater upper body strength change score for CAP (∆%= 13.4 ± 9.1 %) compared to placebo (∆%= 5.8 ± 5.2 %), P = 0.041. CAP had no effect on lower body strength and no supplementation interactions were observed for all cytokines in response to acute resistance exercise (P > 0.05).Conclusion
Chronic Capsiate supplementation combined with resistance training during short period (6 weeks) increased fat-free mass and upper body strength but not inflammatory response and performance in young untrained men.
SUBMITTER: de Moura E Silva VEL
PROVIDER: S-EPMC8218493 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
de Moura E Silva Vilton Emanoel Lopes VEL Cholewa Jason Michael JM Jäger Ralf R Zanchi Nelo Eidy NE de Freitas Marcelo Conrado MC de Moura Rayane Carvalho RC Barros Esmeralda Maria Lustosa EML Antunes Barbara Moura BM Caperuto Erico Chagas EC Ribeiro Sergio Luiz Galan SLG Lira Fabio Santos FS Pereira Dos Santos Marcos Antônio MA Rossi Fabrício Eduardo FE
Journal of the International Society of Sports Nutrition 20210621 1
<h4>Background</h4>Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown. This study investigated changes of chronic Capsiate supplementation on muscular adaptations, inflammatory response and performance in untrained men.<h4>Methods</h4>Twenty untrained men were randomized to ingest 12 mg Capsiate (CAP) or placeb ...[more]