Ontology highlight
ABSTRACT:
SUBMITTER: Đurasevic S
PROVIDER: S-EPMC8226855 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Đurašević Siniša S Pejić Snežana S Grigorov Ilijana I Nikolić Gorana G Mitić-Ćulafić Dragana D Dragićević Milan M Đorđević Jelena J Todorović Vukotić Nevena N Đorđević Neda N Todorović Ana A Drakulić Dunja D Veljković Filip F Pajović Snežana B SB Todorović Zoran Z
Antioxidants (Basel, Switzerland) 20210604 6
Thioacetamide (TAA) is widely used to study liver toxicity accompanied by oxidative stress, inflammation, cell necrosis, fibrosis, cholestasis, and hepatocellular carcinoma. As an efficient free radical's scavenger, C60 fullerene is considered a potential liver-protective agent in chemically-induced liver injury. In the present work, we examined the hepatoprotective effects of two C60 doses dissolved in virgin olive oil against TAA-induced hepatotoxicity in rats. We showed that TAA-induced incre ...[more]