Ontology highlight
ABSTRACT:
SUBMITTER: Hashmi H
PROVIDER: S-EPMC8254545 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Hashmi Hamza H Husnain Muhammad M Khan Ali A Usmani Saad Z SZ
ImmunoTargets and therapy 20210629
The survival outcomes for multiple myeloma have improved several-fold in the past two decades, primarily due to the introduction of therapies with novel mechanisms of action including immunomodulatory agents, proteasome inhibitors, stem cell transplant and monoclonal antibodies in the schema of therapy. Antibody-based therapies targeting the surface marker CD38, namely daratumumab and isatuximab, have emerged as being highly effective as single agents as well as in combination regimens for both ...[more]