Ontology highlight
ABSTRACT:
SUBMITTER: Tzeng HE
PROVIDER: S-EPMC8268073 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Tzeng Huey-En HE Lin Syuan-Ling SL Thadevoos Louis-Anoop LA Ko Chih-Yuan CY Liu Ju-Fang JF Huang Yu-Wen YW Lin Chih-Yang CY Fong Yi-Chin YC Tang Chih-Hsin CH
Cancers 20210703 13
A chondrosarcoma is a common tumor of the soft tissue and bone that has a high propensity to metastasize to distant organs. Nerve growth factor (NGF) is capable of promoting the progression and metastasis of several different types of tumors although the effects of NGF in a chondrosarcoma are not confirmed. Here, we found that the levels of NGF and matrix metalloproteinase-2 (MMP-2) correlated with the tumor stage in patients with a chondrosarcoma. NGF facilitated the MMP-2-dependent cellular mi ...[more]