Red Zn₂SiO₄:Eu³⁺ and Mg₂TiO₄:Mn⁴⁺ nanophosphors for on-site rapid optical detections: Synthesis and characterization.

ABSTRACT: This study reports the synthesis and characterization of the red nanophosphors Zn₂SiO₄:Eu³⁺ (ZSO:Eu³⁺) and Mg₂TiO₄:Mn⁴⁺ (MTO:Mn⁴⁺). The use of phosphors as a fluorescence label for lateral flow immunochromatographic assay (LFIA) has also been described. The optimal photoluminescence (PL) for ZSO:Eu³⁺ was obtained when it was synthesized with 7 mol% of Eu³⁺ and annealed at 1100 °C for 1 h. Long fluorescence lifetime (1.01 ms), high activation energy Ea (0.28 eV), and low PL degeneration (10% at 110 °C) are the characteristics of ZSO:Eu³⁺. MTO:Mn⁴⁺ also exhibited high PL intensity along with a high E _a of 0.32 eV. The emission wavelengths of phosphors are biocompatible with the optical bio-window of tissues. When human immunoglobulin G (human IgG) at a constant concentration of 100 μg/mL was used for detection, the PL ratios of the test line to the control line were 2.15 and 2.28 for the ZSO:Eu³⁺- and MTO:Mn⁴⁺-labeled LFIA, respectively. Thus, the ZSO:Eu³⁺ and MTO:Mn⁴⁺ nanophosphors are capable of human IgG recognition and are the promising candidates as fluorescent labels for on-site rapid optical biodetection.

Supplementary information

The online version contains supplementary material available at 10.1007/s00339-021-04733-0.

SUBMITTER: Yang SH 

PROVIDER: S-EPMC8271324 | biostudies-literature |

REPOSITORIES: biostudies-literature