Ontology highlight
ABSTRACT:
SUBMITTER: Zhao Y
PROVIDER: S-EPMC8286560 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Zhao Yi Y Wang Bingkai B Mostofsky Stewart H SH Caffo Brian S BS Luo Xi X
Biostatistics (Oxford, England) 20210701 3
In this study, we consider the problem of regressing covariance matrices on associated covariates. Our goal is to use covariates to explain variation in covariance matrices across units. As such, we introduce Covariate Assisted Principal (CAP) regression, an optimization-based method for identifying components associated with the covariates using a generalized linear model approach. We develop computationally efficient algorithms to jointly search for common linear projections of the covariance ...[more]