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Clinical features and treatment efficacy for IgG4-related thyroiditis.


ABSTRACT:

Purpose

This study aimed to clarify the clinical features of and evaluate the treatment efficacy for IgG4-related thyroiditis.

Methods

Fourteen IgG4-related thyroiditis patients and 42 randomly matched IgG4-related disease (IgG4-RD) patients without thyroiditis in a prospective cohort at the Peking Union Medical College Hospital (PUMCH) were enrolled from 2011 to 2019. Patient demographics, clinical characteristics, laboratory parameters and treatment efficacy were analysed.

Results

The prevalence of IgG4-related thyroiditis in our cohort was 2.0%. The average patient age was 42.8 ± 14.9 years, and the male: female ratio was 1:1. Goiter (14, 100.0%), hard thyroid (14, 100.0%) and neck compression (5, 35.7%) were the most prevalent onset symptoms observed. IgG4-related

SUBMITTER: Han X 

PROVIDER: S-EPMC8293477 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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