Ontology highlight
ABSTRACT:
SUBMITTER: Beeg M
PROVIDER: S-EPMC8298394 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Beeg Marten M Burti Cesare C Allocati Eleonora E Ciafardini Clorinda C Banzi Rita R Nobili Alessandro A Caprioli Flavio F Garattini Silvio S Gobbi Marco M
Scientific reports 20210722 1
Measurements of serum concentrations of therapeutic antibodies and anti-drug antibodies (ADA) can support clinical decisions for the management of non-responders, optimizing the therapy. In the present study we compared the results obtained by classical ELISA and a recently proposed surface plasmon resonance (SPR)-based immunoassay, in 76 patients receiving infliximab for inflammatory bowel diseases. The two methods indicated very similar serum concentrations of the drug, but there were striking ...[more]