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Different Resource Allocation in a Bacillus subtilis Population Displaying Bimodal Motility.


ABSTRACT: To cope with sudden changes in their environment, bacteria can use a bet-hedging strategy by dividing the population into cells with different properties. This so-called bimodal or bistable cellular differentiation is generally controlled by positive feedback regulation of transcriptional activators. Due to the continuous increase in cell volume, it is difficult for these activators to reach an activation threshold concentration when cells are growing exponentially. This is one reason why bimodal differentiation is primarily observed from the onset of the stationary phase, when exponential growth ceases. An exception is the bimodal induction of motility in Bacillus subtilis, which occurs early during exponential growth. Several mechanisms have been put forward to explain this, including do

SUBMITTER: Syvertsson S 

PROVIDER: S-EPMC8316123 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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