Ontology highlight
ABSTRACT:
SUBMITTER: Jenkins J
PROVIDER: S-EPMC8319809 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Jenkins Joshua J Ishak Mohd I MI Eales Marcus M Gholinia Ali A Kulkarni Satishkumar S Keller Thomas F TF May Paul W PW Nobbs Angela H AH Su Bo B
iScience 20210707 7
To robustly assess the antibacterial mechanisms of nanotopographies, it is critical to analyze the bacteria-nanotopography adhesion interface. Here, we utilize focused ion beam milling combined with scanning electron microscopy to generate three-dimensional reconstructions of <i>Staphylococcus aureus</i> or <i>Escherichia coli</i> interacting with nanotopographies. For the first time, 3D morphometric analysis has been exploited to quantify the intrinsic contact area between each nanostructure an ...[more]