Impact of Specific Bowel Symptoms on Quality of Life in Patients with Midgut Neuroendocrine Tumours.

ABSTRACT:

Introduction

Patients with midgut neuroendocrine tumours (NETs) suffer from decreased health-related quality of life (HRQoL), in large part due to bowel symptoms. However, it is unknown which bowel symptoms affect HRQoL the most. An enhanced understanding of this is essential to better focus treatment on this aspect of the disease. This study aimed to determine which bowel symptoms affect HRQoL the most in patients with midgut NETs.

Methods

Consenting patients with midgut NET completed the Memorial Sloan Kettering Bowel Function Instrument and the HRQoL questionnaire (EORTC QLQ-C30). The correlation between bowel symptoms and HRQoL was analysed using multiple linear regression, adjusting for age, Charlson Comorbidity Index score, presence of metastatic disease, chromogranin

SUBMITTER: Ohlsson H 

PROVIDER: S-EPMC8321966 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature