Feasibility and Repeatability of Handheld Optical Coherence Tomography in Children With Craniosynostosis.

ABSTRACT:

Purpose

To determine whether handheld optical coherence tomography (OCT) is feasible and repeatable in children with craniosynostosis.

Methods

This was a prospective cross-sectional study. Children with syndromic and non-syndromic craniosynostosis 0 to 18 years of age were recruited between February 13, 2020, and October 1, 2020. Main outcome measures included feasibility (patient recruitment and handheld OCT success rates) and repeatability, which were assessed using intraclass correlation coefficients (ICCs) where repeated images of the optic nerve head (ONH) within the same visit were available. ONH parameters used for repeatability analysis included cup depth, width, and area; disc width; rim height; retinal thickness; retinal nerve fiber layer thickness; and Bruch's mem

SUBMITTER: Rufai SR 

PROVIDER: S-EPMC8322722 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature