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Phagocytosis Assay for α-Synuclein Fibril Uptake by Mouse Primary Microglia.

ABSTRACT: Microglia are professional phagocytes in the brain and deficiency in their phagocytic activity plays an important role in Parkinson's disease. This protocol mainly describes the phagocytosis assay for uptake of α-synuclein preformed fibrils, a pathologic form of α-synuclein, by primary microglia.

SUBMITTER: Du C 

PROVIDER: S-EPMC8328642 | biostudies-literature |

REPOSITORIES: biostudies-literature

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