Prognostic factors of adult tuberculous meningitis in intensive care unit: a single-center retrospective study in East China.

ABSTRACT:

Background

Tuberculous meningitis (TBM) is the most lethal form of tuberculosis worldwide. Data on critically ill TBM patients in the intensive care unit (ICU) of China are lacking. We tried to identify prognostic factors of adult TBM patients admitted to ICU in China.

Methods

We conducted a retrospective study on adult TBM in ICU between January 2008 and April 2018. Factors associated with unfavorable outcomes at 28 days were identified by logistic regression. Factors associated with 1-year mortality were studied by Cox proportional hazards modeling.

Results

Eighty adult patients diagnosed with TBM (age 38.5 (18-79) years, 45 (56 %) males) were included in the study. An unfavorable outcome was observed in 39 (49 %) patients and were independently associated with Acut

SUBMITTER: Feng B 

PROVIDER: S-EPMC8353730 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature