Cellular and Clinical Analyses of Autologous Bone Marrow Aspirate Injectate for Knee Osteoarthritis: A Pilot Study.

ABSTRACT:

Introduction

Knee osteoarthritis (OA) is characterized by pain and functional deficits. Common conservative strategies include medications, physical therapy, and intra-articular injections. Recently, treatment using autologous cell injections has increased.

Objective

To characterize the cellular content of bone marrow aspirate (BMA) and to evaluate the effect of intra-articular autologous BMA injections in patients with mild knee OA.

Design

Prospective pilot observational study.

Setting

Academic institution.

Patients

Eleven patients with unilateral or bilateral mild knee OA (15 knees) were included in the cellular analysis. Ten patients (13 knees) were included in the overall (cellular and clinical) analysis.

Interventions

BMA was aspirated from p

SUBMITTER: Wells K 

PROVIDER: S-EPMC8363189 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature