Tuberculosis infection screening in children with close contact: a hospital-based study.

ABSTRACT:

Background

Identifying and prioritizing at-risk populations is critical for pediatric tuberculosis control. We aimed to identify a latent tuberculosis infection (LTBI) screening strategy that is appropriate for the Chinese context among children with different TB exposure levels and to explore its clinical importance.

Methods

During 2013-2015, we enrolled hospitalized children with suspected respiratory infectious disease (RID) for LTBI screening using the tuberculin skin test (TST) and interferon-γ release assay (IGRA) T-SPOT.TB as part of a work up for their RID. Participants with confirmed diagnosis were classified into three subgroups according to level of exposure to TB: no reported contact risk, with household contact risk, and with non-household contact risk.

Resul

SUBMITTER: Sun L 

PROVIDER: S-EPMC8364055 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature