Role of the motor cortex in the generation of classically conditioned eyelid and vibrissae responses.

ABSTRACT: The eyelid motor system has been used for years as an experimental model for studying the neuronal mechanisms underlying motor and cognitive learning, mainly with classical conditioning procedures. Nonetheless, it is not known yet which brain structures, or neuronal mechanisms, are responsible for the acquisition, storage, and expression of these motor responses. Here, we studied the temporal correlation between unitary activities of identified eyelid and vibrissae motor cortex neurons and the electromyographic activity of the orbicularis oculi and vibrissae muscles and magnetically recorded eyelid positions during classical conditioning of eyelid and vibrissae responses, using both delay and trace conditioning paradigms in behaving mice. We also studied the involvement of motor cortex neu

SUBMITTER: Lopez-Ramos JC 

PROVIDER: S-EPMC8371024 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature