Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland.

ABSTRACT: We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.

SUBMITTER: Lynch M 

PROVIDER: S-EPMC8386806 | biostudies-literature |

REPOSITORIES: biostudies-literature