Ontology highlight
ABSTRACT:
SUBMITTER: Canet F
PROVIDER: S-EPMC8389001 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Canet Francisco F Iannantuoni Francesca F Marañon Aránzazu Martínez de AM Díaz-Pozo Pedro P López-Domènech Sandra S Vezza Teresa T Navarro Blanca B Solá Eva E Falcón Rosa R Bañuls Celia C Morillas Carlos C Rocha Milagros M Víctor Víctor M VM
Antioxidants (Basel, Switzerland) 20210730 8
Sodium-glucose co-transporter 2 inhibitors (iSGLT2) have been linked to cardiovascular risk reduction in patients with type 2 diabetes (T2D). However, their underlying molecular mechanisms remain unclear. This study aimed to evaluate the effects of empagliflozin, a novel potent and selective iSGLT-2, on anthropometric and endocrine parameters, leukocyte-endothelium interactions, adhesion molecules, ROS production, and NFkB-p65 transcription factor expression. According to standard clinical proto ...[more]