Ontology highlight
ABSTRACT:
SUBMITTER: Cheng AJ
PROVIDER: S-EPMC8392418 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Cheng Ann-Joy AJ You Guo-Rung GR Lee Che-Jui CJ Lu Ya-Ching YC Tang Shang-Ju SJ Huang Yi-Fang YF Huang Yu-Chen YC Lee Li-Yu LY Fan Kang-Hsing KH Chen Yen-Chao YC Huang Shiang-Fu SF Chang Joseph Tung-Chieh JT
Diagnostics (Basel, Switzerland) 20210804 8
<h4>Background</h4>Liquid biopsy is a rapidly growing field, for it may provide a minimally invasive way to acquire pathological data for personalized medicine. This study developed a systemic strategy to discover an effective salivary biomarker for early detection of patients with head-neck squamous carcinoma (HNSC) and oral precancer lesion (OPC).<h4>Methods</h4>A total of 10 miRNAs were examined in parallel with multiple independent cohorts. These included a training set of salivary samples f ...[more]