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SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy.


ABSTRACT:

SUBMITTER: Gomes I 

PROVIDER: S-EPMC8397543 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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SARS-CoV-2 infection of the central nervous system in a 14-month-old child: A case report of a complete autopsy.

Gomes Ismael I   Karmirian Karina K   Oliveira Júlia T JT   Pedrosa Carolina da S G CDSG   Mendes Mayara Abud MA   Rosman Fernando Colonna FC   Chimelli Leila L   Rehen Stevens S  

Lancet regional health. Americas 20210828


<h4>Background</h4>Neurological and other systemic complications occur in adults with severe COVID-19. Here we describe SARS-CoV-2 infection complicated by neuroinvasion in the <i>post-mortem</i> tissues of a child.<h4>Methods</h4>We performed a complete autopsy of a 14-month-old child who died of COVID-19 pneumonitis. Histological sections of multiple organs were stained with haematoxylin and eosin. Luxol fast blue staining for myelin and immunohistochemistry were performed in selected areas of  ...[more]

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