Ontology highlight
ABSTRACT:
SUBMITTER: Arce A
PROVIDER: S-EPMC8419261 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Arce Anibal A Guzman Chavez Fernando F Gandini Chiara C Puig Juan J Matute Tamara T Haseloff Jim J Dalchau Neil N Molloy Jenny J Pardee Keith K Federici Fernán F
Frontiers in bioengineering and biotechnology 20210823
Cell-free gene expression systems have emerged as a promising platform for field-deployed biosensing and diagnostics. When combined with programmable toehold switch-based RNA sensors, these systems can be used to detect arbitrary RNAs and freeze-dried for room temperature transport to the point-of-need. These sensors, however, have been mainly implemented using reconstituted PURE cell-free protein expression systems that are difficult to source in the Global South due to their high commercial co ...[more]