Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC8420371 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Zhang Xinyuan X Yang Yuching Y Grimstein Manuela M Liu Guansheng G Kitabi Eliford E Fan Jianghong J Wang Ying-Hong YH Earp Justin J Weaver James L JL Zhu Hao H Liu Jiang J Reynolds Kellie S KS Huang Shiew-Mei SM Wang Yaning Y
CPT: pharmacometrics & systems pharmacology 20210801 9
A critical step to evaluate the potential in vivo antiviral activity of a drug is to connect the in vivo exposure to its in vitro antiviral activity. The Anti-SARS-CoV-2 Repurposing Drug Database is a database that includes both in vitro anti-SARS-CoV-2 activity and in vivo pharmacokinetic data to facilitate the extrapolation from in vitro antiviral activity to potential in vivo antiviral activity for a large set of drugs/compounds. In addition to serving as a data source for in vitro anti-SARS- ...[more]