Ontology highlight
ABSTRACT:
SUBMITTER: Fores-Martos J
PROVIDER: S-EPMC8433453 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Fores-Martos Jaume J Cervera-Vidal Raimundo R Sierra-Roca Julia J Lozano-Asencio Carlos C Fedele Vita V Cornelissen Sten S Edvarsen Hege H Tadeo-Cervera Irene I Eroles Pilar P Lluch Ana A Tabares-Seisdedos Rafa R Falcó Antonio A Van't Veer Laura J LJ Schmidt Marjanka M Quigley David A DA Børresen-Dale Anne-Lise AL Kristensen Vessela N VN Balmain Allan A Climent Joan J
NPJ breast cancer 20210910 1
Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including sleep disorders and cancer. In particular, the long allele of a variable number of tandem repeat (VNTR) polymorphism has been previously linked to an increased risk of breast cancer. Here we carried out a combined germline and somatic genetic analysis of the role of the PER3<sup>VNRT</sup> polymorphism in breast cancer. The combined data from 8284 individuals showed a non-significant trend toward ...[more]