Ontology highlight
ABSTRACT:
SUBMITTER: Lee M
PROVIDER: S-EPMC8455597 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Lee Maria M Fatouros-Bergman Helena H Plavén-Sigray Pontus P Ikonen Victorsson Pauliina P Sellgren Carl M CM Erhardt Sophie S Flyckt Lena L Farde Lars L Cervenka Simon S
NPJ schizophrenia 20210921 1
Cognitive impairment is an important predictor of disability in schizophrenia. Dopamine neurotransmission in cortical brain regions has been suggested to be of importance for higher-order cognitive processes. The aim of this study was to examine the relationship between extrastriatal dopamine D2-R availability and cognitive function, using positron emission tomography and the high-affinity D2-R radioligand [<sup>11</sup>C]FLB 457, in an antipsychotic-naive sample of 18 first-episode psychosis pa ...[more]