Unknown

Dataset Information

0

POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

ABSTRACT:

SUBMITTER: Chen YX 

PROVIDER: S-EPMC8473642 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

Chen Yan-Xing YX   Wang Zi-Xian ZX   Yuan Shu-Qiang SQ   Jiang Teng-Jia TJ   Huang You-Sheng YS   Xu Rui-Hua RH   Wang Feng F   Zhao Qi Q  

Clinical and translational medicine 20210901 9

Similar Datasets

Unknown Low frequency of POLD1 and POLE exonuclease domain variants in patients with multiple colorectal polyps.
| S-EPMC6465667 | biostudies-literature
Unknown Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1.
| S-EPMC10580551 | biostudies-literature
Unknown POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East.
| S-EPMC7434734 | biostudies-literature
Unknown Non-Exonuclease Domain POLE Mutations Associated with Immunotherapy Benefit.
| S-EPMC8914489 | biostudies-literature
Unknown Functional landscapes of POLE and POLD1 mutations in checkpoint blockade-dependent antitumor immunity.
| S-EPMC10181095 | biostudies-literature
Unknown Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.
| S-EPMC10812383 | biostudies-literature
Unknown Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.
| S-EPMC7018097 | biostudies-literature
Unknown Distinctive genomic characteristics in <i>POLE/POLD1</i>-mutant cancers can potentially predict beneficial clinical outcomes in patients who receive immune checkpoint inhibitor.
| S-EPMC7867935 | biostudies-literature
Unknown Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1.
| S-EPMC5943186 | biostudies-literature
Unknown Role of POLE and POLD1 in familial cancer.
| S-EPMC7708298 | biostudies-literature