Decrease in Serum Urate Level Is Associated With Loss of Visceral Fat in Male Gout Patients.

ABSTRACT:

Objective

To clarify the relationship between serum urate (SU) decrease and visceral fat area (VFA) reduction in patients with gout.

Methods

We retrospectively analyzed 237 male gout patients who had two sets of body composition and metabolic measurements within 6 months. Subjects included had all been treated with urate-lowering therapy (ULT) (febuxostat 20-80 mg/day or benzbromarone 25-50 mg/day, validated by the medical record). All patients were from the specialty gout clinic of The Affiliated Hospital of Qingdao University. The multiple linear regression model evaluated the relationship between change in SU [ΔSU, (baseline SU) - (final visit SU)] and change in VFA [ΔVFA, (baseline VFA) - (final visit VFA)].

Results

ULT resulted in a mean (standard deviation) decr

SUBMITTER: Ran Z 

PROVIDER: S-EPMC8476917 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature