Ontology highlight
ABSTRACT:
SUBMITTER: Ruan Y
PROVIDER: S-EPMC8477804 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Ruan Yongsheng Y Ogana Heather H Gang Eunji E Kim Hye Na HN Kim Yong-Mi YM
Advances in experimental medicine and biology 20210101
Dysregulated Wnt signaling plays a central role in initiation, progression, and metastasis in many types of human cancers. Cancer development and resistance to conventional cancer therapies are highly associated with the tumor microenvironment (TME), which is composed of numerous stable non-cancer cells, including immune cells, extracellular matrix (ECM), fibroblasts, endothelial cells (ECs), and stromal cells. Recently, increasing evidence suggests that the relationship between Wnt signaling an ...[more]