Effect of guidewire insertion in fractional flow reserve procedure for real geometry using computational fluid dynamics.

ABSTRACT:

Background

Coronary artery disease is an abnormal contraction of the heart supply blood vessel. It limits the oxygenated blood flow to the heart. Thus, diagnosing its severity helps physicians to select the appropriate treatment plan. Fractional flow reserve (FFR) is the most accurate method to pinpoint the stenosis severity. However, inserting the guidewire across stenosis may cause a false overestimation of severity.

Methods

To estimate the errors due to guidewire insertion, reconstructed three-dimensional coronary artery geometry from a patient-specific scan is used. A comprehensive three-dimensional blood flow model is developed. Blood is considered non-Newtonian and the flow is pulsatile. The model is numerically simulated using realistic boundary conditions.

Results

SUBMITTER: Abuouf Y 

PROVIDER: S-EPMC8479905 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature