The association of oxidative stress biomarkers with type 2 diabetes mellitus: A systematic review and meta-analysis.

ABSTRACT:

Background and aims

Oxidative stress plays a major role in the development of type 2 diabetes mellitus (T2DM). However, there were controversial outcomes in the literature between the association of oxidative stress biomarkers and T2DM. The purpose of this systematic review and meta-analysis was to critically examine the association of oxidative stress biomarkers with T2DM.

Methods

We systematically searched different electronic databases including PubMed/Medline, EMBASE, ScienceDirect, Web of Science, and Cochrane Library to find the relevant studies up to May 2021. The pooled standard mean difference (SMD) with a 95% confidence interval (CI) was used to define the variation between the study groups.

Results

A total of 22 case-control studies with 2853 subjects (1667

SUBMITTER: Banik S 

PROVIDER: S-EPMC8485598 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature