Ontology highlight
ABSTRACT:
SUBMITTER: Charroux B
PROVIDER: S-EPMC84859 | biostudies-literature | 1999 Nov
REPOSITORIES: biostudies-literature
Charroux B B Angelats C C Fasano L L Kerridge S S Vola C C
Molecular and cellular biology 19991101 11
We have characterized the Drosophila bancal gene, which encodes a Drosophila homologue of the vertebrate hnRNP K protein. The bancal gene is essential for the correct size of adult appendages. Reduction of appendage size in bancal mutant flies appears to be due mainly to a reduction in the number of cell divisions in the imaginal discs. Transgenes expressing Drosophila or human hnRNP K are able to rescue weak bancal phenotype, showing the functional similarity of these proteins in vivo. High lev ...[more]