Inter-individual variability in structural brain development from late childhood to young adulthood.

ABSTRACT: A fundamental task in neuroscience is to characterize the brain's developmental course. While replicable group-level models of structural brain development from childhood to adulthood have recently been identified, we have yet to quantify and understand individual differences in structural brain development. The present study examined inter-individual variability and sex differences in changes in brain structure, as assessed by anatomical MRI, across ages 8.0-26.0 years in 269 participants (149 females) with three time points of data (807 scans), drawn from three longitudinal datasets collected in the Netherlands, Norway, and USA. We further investigated the relationship between overall brain size and developmental changes, as well as how females and males differed in change variability ac

SUBMITTER: Mills KL 

PROVIDER: S-EPMC8489572 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature